A fasting regimen can be positive to reduce inflammation and to generally combat chronic inflammatory diseases and the pathologies that can result from them. A new study, this time published on Cell, highlights the positive aspects of fasting and in general of the strong caloric restrictions that can be applied to a normal diet periodically.
Miriam Merad, the author of the study and director of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai, showed that intermittent fasting in mice promotes the reduction of the release of pro-inflammatory cells called “monocytes” in the blood.
During the fasting period, these cells appeared in mice to enter a sort of “sleep,” which led them to reduce their inflammatory action compared to the same cells of the mice that had instead taken food. According to Merad herself, “Monocytes are highly inflammatory immune cells that can cause severe tissue damage and the population has seen an increasing amount in their blood circulation due to the eating habits that humans have acquired over the last few centuries.”
The same researcher also admits that the study of the anti-inflammatory effects of fasting can have an “enormous potential” – if the molecular mechanisms by which fasting acts on inflammatory diseases are accurately discovered, new therapeutic strategies could be developed to mimic this process.